Course Director：韩杰、里程楠、刘新民、王斌、王坚刚

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讨论嘉宾

学习目标： 1. 全面综合管理： 明确单纯主动脉瓣反流（Pure AR）患者合并主动脉根部及升主动脉病变时的综合诊疗原则，厘清同期外科手术与分期介入的临床边界。 2. 多维精准评估： 掌握基于多模态影像学参数（超声心动图、心脏CT/MRI等），结合患者无症状期左心室容量与功能变化，精准把握单纯AR的早期干预时机。 3. 追踪微创前沿： 熟悉经导管主动脉瓣置换（TAVR）在无钙化单纯AR治疗中所面临的锚定难题，掌握最新AR专用介入器械的技术突破点与解剖适应证。

讨论建议： 1. 专用 vs 传统器械抉择： 针对无钙化或少钙化的单纯AR，目前在临床实践中，使用传统TAVR器械（通过超大尺寸或特殊锚定技巧）与使用新型AR专用介入器械相比，两者的安全性与远期获益有何异同？ For non-calcified or minimally calcified pure AR in clinical practice, what are the differences in safety and long-term outcomes between utilizing traditional TAVR devices (via oversizing or special anchoring techniques) versus next-generation, AR-dedicated transcatheter devices? 2. 主动脉根部病变兼顾： 当单纯AR患者合并升主动脉轻中度扩张（未达传统外科手术指征）时，内外科团队在制定干预策略时如何兼顾瓣膜反流与主动脉壁的潜在进展风险？ When a patient with pure AR presenting with mild-to-moderate ascending aortic dilation (not yet meeting traditional surgical criteria), how should the heart team balance treating the valvular regurgitation while managing the potential risk of aortic wall progression? 3. 无症状期的干预时机： 临床上如何更早地捕捉“无症状单纯AR”患者心室功能损害的不可逆临界点，以推动干预时机从“延迟等待”向“精准提前”转变？ How can clinicians better capture the irreversible tipping point of ventricular dysfunction in "asymptomatic pure AR" patients, driving the shift in intervention timing from "watchful waiting" to "precise early intervention"?

单纯AR治疗中的主动脉根部与升主动脉综合管理策略 Comprehensive Management Strategies for the Aortic Root and Ascending Aorta in Pure AR Treatment

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单纯AR干预时机：症状、心脏结构与影像学参数的精准把握 Precise Determination of Intervention Timing for Pure AR: Insights from Symptoms, Cardiac Structure, and Imaging Parameters

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Guideline-Driven Surgery in AR: Too Late?

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内外科医生共同面对的瓣膜材料新纪元 A New Era of Valve Materials Faced Jointly by Cardiologists and Cardiac Surgeons

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